summaryrefslogtreecommitdiff
path: root/macros/latex/contrib/nih/example-biosketch.tex
blob: f001cc4e8344b62d939e858cf4a3e28031d160f7 (plain)
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
% This example file for NIH biographical sketches was originally written
% by Bruce Donald (http://www.cs.duke.edu/brd/).
% 
% You may freely use, modify and/or distribute this file.
% 
\documentclass[11pt]{nih}
%\documentclass[12pt]{nih-times}
% last revision:
\def\mydate{2006-09-16 17:10:33 karl}
%\usepackage[dvips]{graphicx}
%\usepackage{psfrag}
\usepackage{color}
%\usepackage{boxedminipage}
\usepackage{amsfonts}
\usepackage{denselists}

\long\def\gobble#1{}

\long\def\MEMS#1{}

%Note from brd
\long\def\todo#1{}
\def\ICRA{IEEE International Conference on Robotics and Automation (ICRA)}

\def\cbk#1{[{\em #1}]}

\def\degree{$^\circ$}
\def\R{\mathbb{R}}
\def\Fscr{\mathcal{F}}
\def\set#1{{\{#1\}}}
\def\edge{\!\rightarrow\!}
\def\dedge{\!\leftrightarrow\!}

\def\Jigsaw{{\sc Jigsaw}}
\def\ahelix{\ensuremath{\alpha}-helix}
\def\ahelices{\ensuremath{\alpha}-helices}
\def\ahelical{$\alpha$-helical}
\def\bstrand{\ensuremath{\beta}-strand}
\def\bstrands{\ensuremath{\beta}-strands}
\def\bsheet{\ensuremath{\beta}-sheet}
\def\bsheets{\ensuremath{\beta}-sheets}
\def\hone{\ensuremath{^1}\rm{H}}
\def\htwo{$^{2}$H}
\def\cthir{\ensuremath{^{13}}\rm{C}}
\def\nfif{\ensuremath{^{15}}\rm{N}}
\def\hn{\rm{H}\ensuremath{^\mathrm{N}}}
\def\hnone{\textup{H}\ensuremath{^1_\mathrm{N}}}
\def\ca{\rm{C}\ensuremath{^\alpha}}
\def\catwel{\ensuremath{^{12}}\rm{C}\ensuremath{^\alpha}}
\def\ha{\rm{H}\ensuremath{^\alpha}}
\def\cb{\rm{C}\ensuremath{^\beta}}
\def\hb{\rm{H}\ensuremath{^\beta}}
\def\hg{\rm{H}\ensuremath{^\gamma}}
\def\dnn{\ensuremath{d_{\mathrm{NN}}}}
\def\dan{\ensuremath{d_{\alpha \mathrm{N}}}}
\def\jconst{\ensuremath{^{3}J_{\mathrm{H}^{\mathrm{N}}\mathrm{H}^{\alpha}}}}

\def\cbfb{CBF-$\beta$}

\newtheorem{defn}{Definition}
\newtheorem{claim}{Claim}

\newenvironment{closeenumerate}{\begin{list}{\arabic{enumi}.}{\topsep=0in\itemsep=0in\parsep=0in\usecounter{enumi}}}{\end{list}}
\def\CR{\hspace{0pt}}           % ``invisible'' space for line break

%\long\def\efforta mount#1{#1}
\long\def\effortamount#1{}

\begin{document}

%\setcounter{page}{20} % or whatever
\setcounter{page}{7} % or whatever

%\newsec{Biographical Sketch: Bruce Randall Donald}
\def\vp{\vphantom{\Large{O}}}
\def\Vp{\vphantom{\LARGE{O}}}


\subsubsection*{Biographical Sketch}

%\gobble{

\begin{tabular}{|l|l|}
\hline
\Vp{\sf Name} & {\sf Position Title}\\
\hline
\Vp \ \ {\bf Bruce R.~Donald, Ph.D.} & \ 
 {\bf   Professor of Computer Science and Biochemistry}\\
\gobble{{\bf   William and Sue Gross Professor  }\\
 & \ \ \ \ \ \ {\bf  of Computer Science and Biochemistry (as of 8/1/2006)}\\}
\hline
\end{tabular}

%}

\subsubsection*{Education/Training}

\begin{tabular}{|l|c|c|l|}
\hline
\Vp{\sf INSTITUTION} & 	{\sf DEGREE} &
     {\sf YEAR} & {\sf	FIELD OF STUDY}\\
\hline
\hline
\Vp Yale University	& B.A.	& 1980	& \\
\hline
\Vp Massachusetts Institute of Technology	& S.M.&	1984 &	Electrical Engineering \& Computer Science\\
\hline
\Vp Massachusetts Institute of Technology &	Ph.D.	&1987&
Computer Science\\
\hline
\end{tabular}

\bigskip

\gobble{
\noindent
\begin{Description}
\item[]
Ph.D.~Advisor: Tom\'as Lozano-P\'erez, MIT Artificial Intelligence
Laboratory and Department of Electrical Engineering \& Computer Science.
\end{Description}
}

\subsubsection*{A. Research and Professional Experience}

\underline{Professional Experience}

\def\myitem{\ $\bullet$\ }

 %\def\parens#1{({#1})}
\def\parens#1{{#1}:}

%\begin{Description}
{\myitem} \parens{1978-84} Research Analyst,
Laboratory for Computer Graphics and Spatial
Analysis, GSD, Harvard University.  
{\myitem} \parens{1984} Research Staff, Artificial Intelligence Laboratory, MIT.
{\myitem} \parens{1982-1987} Graduate student, Artificial Intelligence Laboratory and Department of EECS, MIT. 
{\myitem} \parens{1987-1993} Assistant Professor; 
\parens{1993-1998} Associate Professor (with tenure), Computer Science Department, Cornell University.
{\myitem} \parens{1995-1996} Consultant and Contractor, Interval Research Corporation, Palo Alto, CA.
{\myitem} \parens{1994-1996} Visiting Professor, Computer Science Department,
Stanford. 
{\myitem} \parens{1997-1999} Associate Professor (with tenure);
  \parens{1999-2006} Professor of Computer Science,
  Dartmouth College.
\gobble{{\myitem} \parens{1998} Founder, M.D.-Ph.D.~Program in Computational Biology, Dartmouth College and
Dartmouth Medical School.}
{\myitem} \parens{1999-2006} M.D.-Ph.D.~Committee, Dartmouth College and
Dartmouth Medical School.
{\myitem} \parens{2000} Conference chair, Int'l.~Workshop on Algorithmic
Foundations of Robotics.
{\myitem} 11 NSF Advisory Panels (1990-2003).
{\myitem} \parens{2000-2001} Visiting Scientist, Artificial Intelligence Laboratory and Department of EECS, MIT.
{\myitem} \parens{2000-2002} Scientific Advisory Board, Carta
Proteomics, Inc. (now ExSAR). 
{\myitem} \parens{2000-2006} Member, Dartmouth Center for Structural
Biology and Computational Chemistry.
{\myitem} \parens{2000-2006} Adjunct Professor of Chemistry, Dartmouth.
{\myitem} \parens{2002-2006} Adjunct Professor of Biological Sciences, Dartmouth.
{\myitem} \parens{2002, 2004, 2005} {\em Ad hoc} Member, NIH Study Sections (BBCA,
 ALY, ZRG1 CFS).
{\myitem}  \parens{2003--2006} Joan and Edward Foley Professor, Dartmouth.
{\myitem}\parens{2006--now} William and Sue Gross Professor of Computer
Science, Duke University. 
{\myitem}\parens{2006--now}
Professor of Biochemistry, School of Medicine, Duke University Medical Center.

%\end{Description}

\noindent\underline{Honors and Awards}

%\begin{Description}

{\myitem} \parens{1979} Phi Beta Kappa; \parens{1980} Distinction in the Major, Yale University.
{\myitem} \parens{1980} Graduated  {\em Summa Cum Laude,} Yale.
{\myitem} \parens{1985-1987} NASA/JPL Graduate Student Researcher Fellowship.
{\myitem} \parens{1989-1994} NSF Presidential Young Investigator.
{\myitem} \parens{1997-2000} NSF Challenges in Computer and Information Science and Engineering Grant.	
{\myitem} \parens{2001} Guggenheim Fellow, {\em
``Algorithms in Structural Proteomics."}
{\myitem} \parens{2002} Distinguished Lectures, Robert Mueller-Thuns
(Univ.~Illinois, Urbana-Champaign); Triangle (UNC Chapel Hill, Duke
\& N.C.~State).

%\end{Description}

\def\mystar{{$\star$}}

%\subsubsection*{Selected Peer-reviewed Publications (from a list of
%159 total, with 28 in 2003-4). }

\medskip

\noindent{\bf B. Selected Peer-reviewed Publications (from a list of
176 total, with 19 in 2005--6)}\gobble{\\ {\sf Publications available online at
  {\tt
  www.cs.dartmouth.edu/brd/Research/Bio/}} }

\vspace*{-0.1in}

\gobble{{{\mystar} {\em Note: In Computer Science, certain conferences
(Marked with a $\star$) are are highly selective and rigorously
refereed, often by 3 reviewers plus the conference chairs. Conference
papers are published not as one-page abstracts, but as 8-12 page full
papers (in 10pt double-column format). For this reason, conference
papers are considered primary publications in the field.  Selectivity
can be roughly quantitated by the acceptance rate.}}}

\def\Nospacing{\itemsep=0pt\topsep=0pt\partopsep=0pt\parskip=0pt\parsep=0pt}

\makeatletter
\def\thebibliography#1{\list
{[\arabic{enumiv}]}{\settowidth\labelwidth{[#1]}\leftmargin\labelwidth
\advance\leftmargin\labelsep
\usecounter{enumiv}\Nospacing}
\def\newblock{\hskip .11em plus .33em minus .07em}
\sloppy\clubpenalty4000\widowpenalty4000
\sfcode`\.=1000\relax
}
\let\endthebibliography=\endlist
\makeatother

%%%%%%% begin papers/biblio
%\begin{thebibliography}{10}

\def\th{$^{\rm{th}}$}

%\def\mybibitem#1#2{\bibitem{#1}{#2}}
\def\brd{B.~R. Donald}
%\def\brd{{\bf B.~R. Donald}}

\def\mybibitem#1{\item}
\begin{Enumerate}

%\input{papers-r01}
%% %\begin{thebibliography}{10}

%% \def\th{$^{\rm{th}}$}

%% %\def\mybibitem#1#2{\bibitem{#1}{#2}}

%% \def\mybibitem#1{\item}
%% \begin{Enumerate}

\bibitem{KapurMundyDonald92}
B.~R. Donald, D.~Kapur, and J.~Mundy.
\newblock {\em Symbolic and Numerical Computation for Artificial Intelligence}.
\newblock Academic Press, Harcourt Jovanovich, London, 1992.

\bibitem{CannyDonaldReifXavier93}
B.~R. Donald, P.~Xavier, J.~Canny, and J.~Reif.
\newblock Kinodynamic motion planning.
\newblock {\em Journal of the ACM}, 40(5):1048--1066, 1993.

\bibitem{jcb00-jigsaw}
C.~Bailey-Kellogg, A.~Widge, J.~J. {Kelley III}, M.~J. Berardi, J.~H.
  Bushweller, and {\brd}.
\newblock The {NOESY} {Jigsaw}: Automated protein secondary structure and
  main-chain assignment from sparse, unassigned {NMR} data.
\newblock {\em Jour. Comp. Biol.}, 3-4(7):537--558, 2000.

\bibitem{jcb00-sar}
C.~Bailey-Kellogg, J.~J. {Kelley III}, C.~Stein, and {\brd}.
\newblock Reducing mass degeneracy in {SAR} by {MS} by stable isotopic
  labeling.
\newblock {\em Jour. Comp. Biol.}, 8(1):19--36, 2001.

\gobble{
\bibitem{icra01}
C.~Bailey-Kellogg, J.~J. {Kelley III}, R.~Lilien, and {\brd}.
\newblock Physical geometric algorithms for structural molecular biology.
\newblock In {\em the Special Session on Computational Biology \& Chemistry,
  {\it Proc.~{IEEE} Int'l Conf. on Robotics and Automation
  ({ICRA})}}, pp.~940--947, May 2001.
}

\bibitem{recomb01}
C.~Langmead and {\brd}.
\newblock Extracting structural information using time-frequency analysis of
  protein {NMR} data.
\newblock In {\em Proc.~5{\th}  Int'l.~Conf.~on
  Research in Computational Molecular Biology (RECOMB)}, pp.~164--175. ACM
  Press, April 2001.

\gobble{
\bibitem{csb02}
C.~Langmead, C.~R. McClung, and {\brd}.
\newblock A maximum entropy algorithm for rhythmic analysis of genome-wide
  expression patterns.
\newblock In {\em Proc.~IEEE Computer Society Bioinformatics
  Conference (IEEE CSB)}, pp.~237--245, August 2002.
}

\bibitem{jcb-rage}
C.~Langmead, A.~Yan, C.~R. McClung, and {\brd}.
\newblock Phase-independent rhythmic analysis of genome-wide expression
  patterns.
\newblock {\em Journal of Computational Biology}, 10(3-4):521--536, 2003.

\bibitem{jcb-fld03}
R.~Lilien, H.~Farid, and {\brd}.
\newblock Probabilistic disease classification of expression-dependent
  proteomic data from mass spectrometry of human serum.
\newblock {\em Journal of Computational Biology}, 10(6):925--946, 2003.

\bibitem{recomb03}
C.~Langmead, A.~Yan, R.~Lilien, L.~Wang, and {\brd}.
\newblock A polynomial-time nuclear vector replacement algorithm for automated
  {NMR} resonance assignments.
\newblock In {\em Proc.~7{\th} Int'l.~Conf.~on
  Research in Computational Molecuar Biology (RECOMB)}, pp.~176--187,
  Berlin, Germany, April 2003. ACM Press.

\bibitem{ieeecsb-langmead03}
C.~Langmead and {\brd}.
\newblock 3{D} structural homology detection via unassigned residual dipolar
  couplings.
\newblock In {\em Proc.~{IEEE} Computer Society Bioinformatics
  Conference ({CSB})}, pp.~209--217, Stanford, Aug.~2003.

\bibitem{oneil-jbc03}
R.~O'Neil, R.~Lilien, {\brd}, R.~Stroud, and A.~Anderson.
\newblock Phylogenetic classification of protozoa based on the structure of the
  linker domain in the bifunctional enzyme, dihydrofolate reductase-thymidylate
  synthase.
\newblock {\em Jour. Biol. Chem.}, 278(52):52980--52987, 2003.

\bibitem{oneil-jem03}
R.~O'Neil, R.~Lilien, {\brd}, R.~Stroud, and A.~Anderson.
\newblock The crystal structure of dihydrofolate reductase-thymidylate synthase
  from {{\em Cryptosporidium hominis}} reveals a novel architecture for the
  bifunctional enzyme.
\newblock {\em Jour. Eukaryotic Microbiology}, 50(6):555--556, 2003.

\gobble{
\bibitem{ieeecsb03-wang}
L.~Wang, R.~Mettu, R.~Lilien, and {\brd}.
\newblock An exact algorithm for determining protein backbone structure from
  {NH} residual dipolar couplings.
\newblock In {\em Proc.~{IEEE} Computer Society Bioinformatics
  Conference ({CSB})}, pp.~611--612, Stanford, August 2003.
}

\bibitem{langmead-jbnmr04}
C.~Langmead and {\brd}.
\newblock An expectation/maximization nuclear vector replacement algorithm for
  automated {NMR} resonance assignments.
\newblock {\em Jour. Biomolecular {NMR}}, 29(2):111--138, 2004.

\bibitem{wang-jbnmr03}
L.~Wang and {\brd}.
\newblock Exact solutions for internuclear vectors and backbone dihedral angles
  from {NH} residual dipolar couplings in two media, and their application in a
  systematic search algorithm for determining protein backbone structure.
\newblock {\em Jour. Biomolecular {NMR}}, 29(3):223--242, 2004.

\bibitem{langmead-jcb04}
C.~Langmead, A.~Yan, R.~Lilien, L.~Wang, and {\brd}.
\newblock A polynomial-time nuclear vector replacement algorithm for automated
  {NMR} resonance assignments.
\newblock {\em Jour. Comp. Biol.}, 11(2-3):277--298, 2004.

\bibitem{recomb-04}
R.~Lilien, B.~Stevens, A.~Anderson, and {\brd}.
\newblock A novel ensemble-based scoring and search algorithm for protein
  redesign, and its application to modify the substrate specificity of the
  gramicidin synthetase {A} phenylalanine adenylation enzyme.
\newblock In {\em Proc.~Eighth Annual International Conference on
  Research in Computational Molecular Biology ({RECOMB})}, pp.~46--57, San
  Diego, March 2004.

\bibitem{lilien-acd04}
R.~Lilien, C.~Bailey-Kellogg, A.~Anderson, and {\brd}.
\newblock {A subgroup algorithm to identify cross-rotation peaks consistent
  with non-crystallographic symmetry}.
\newblock {\em Acta Crystallographica Section D: Biological Crystallography},
  60(6):1057--1067, Jun 2004.

\bibitem{LangmeadDonald-csb04}
C.~Langmead and {\brd}.
\newblock High-throughput 3{D} structural homology detection via {NMR}
  resonance assignment.
\newblock In {\em Proc.~{IEEE} Computational Systems
  Bioinformatics Conference ({CSB})}, pp.~278--289, Stanford, CA, August
  2004.

\gobble{
\bibitem{Dartmouth:TR2004-492}
R.~Lilien, M.~Sridharan, and {\brd}.
\newblock {Identification of Novel Small Molecule Inhibitors of Core-Binding
  Factor Dimerization by Computational Screening against NMR Molecular
  Ensembles}.
\newblock Technical Report TR2004-492, Dartmouth College, Computer Science,
  Hanover, NH, March 2004.
}

\bibitem{WangDonald-csb04}
L.~Wang and {\brd}.
\newblock Analysis of a systematic search-based algorithm for determining
  protein backbone structure from a minimal number of residual dipolar
  couplings.
\newblock In {\em Proc.~{IEEE} Computational Systems
  Bioinformatics Conference ({CSB})}, pp.~319--330, Stanford, CA, August
  2004.

\bibitem{ismb05}
R.~Mettu, R.~Lilien, and B.~R. Donald.
\newblock High-throughput inference of protein-protein interfaces from
  unassigned {NMR} data.
\newblock {\em Bioinformatics}, 2005; {\bf{21}}(Suppl.~1):i292--i301.   
\gobble{special issue from papers presented at the 2005 Int'l.~Conf.~on
Intelligent Systems for Molecular Biology, Detroit, MI) }

\mybibitem{jcb04-NRPS}
R.~Lilien, B.~Stevens, A.~Anderson, and {\brd}.
\newblock A novel ensemble-based scoring and search algorithm for protein
  redesign, and its application to modify the substrate specificity of the
  gramicidin synthetase {A} phenylalanine adenylation enzyme.
\newblock {\em Journal of Computational Biology} 2005; {\bf{12}}(6-7):740--761.

\mybibitem{csb05-noe}
L.~Wang and B.~R. Donald.
\newblock An efficient and accurate algorithm for assigning nuclear
  {Overhauser} effect restraints using a rotamer library ensemble and residual
  dipolar couplings.
\newblock In {\em Proceedings of the {IEEE} Computational Systems
  Bioinformatics Conference ({CSB})}, pp.~189--202,
Stanford, CA, August 2005.

\mybibitem{csb05-poly}
L.~Wang, R.~Mettu, and B.~R. Donald.
\newblock An algebraic geometry approach to protein backbone structure
  determination from {NMR} data.
\newblock In {\em Proceedings of the {IEEE} Computational Systems
  Bioinformatics Conference ({CSB})}, pp.~235--246, Stanford, CA,
August 2005.

\gobble{
\mybibitem{recomb-06}
I.~Georgiev, R.~Lilien, and B.~R. Donald.
\newblock A novel minimized dead-end elimination criterion and its application
  to protein redesign in a hybrid scoring and search algorithm for computing
  partition functions over molecular ensembles.
\newblock In {\em Proc.~Tenth Ann.~Intl.~Conf.~on
  Research in Computational Molecular Biology (RECOMB)}, pp. 530--545,
  Venice, Italy, April 2006. Springer Berlin, Lecture Notes in
  Computer Science, LNBI 3909.
}

\bibitem{ismb06}
I.~Georgiev, R.~Lilien, and B.~R. Donald.
\newblock Improved pruning algorithms and divide-and-conquer strategies for
  dead-end elimination, with application to protein design.
\newblock {\em Bioinformatics} 2006; {\bf{22}}(14):e174--183.
\newblock Special issue on papers from the Int'l Conf. on Intelligent
  Sys. for Mol. Biol. ({ISMB 2006}), Fortaleza, Brazil.

\bibitem{csb06}
L.~Wang and B.~R. Donald.
\newblock A data-driven, systematic search algorithm for structure
  determination of denatured or disordered proteins.
\newblock In {\em Proceedings of the LSS Computational Systems Bioinformatics
  Conference ({CSB})}, Stanford, CA, August 2006.
 Pages 67-78. ISBN 1-86094-700-X.

\bibitem{jcb-poly06}
L.~Wang, R.~Mettu, and B.~R. Donald.
\newblock A polynomial-time algorithm for {\em de novo} protein backbone
  structure determination from {NMR} data.
\newblock {\em Journal of Computational Biology}, 2006.
\newblock In press.

\bibitem{proteins06}
S.~Potluri, A.~Yan, B.~R. Donald, and C.~Bailey-Kellogg.
\newblock Structure determination of symmetric homo-oligomers by a complete
  search of symmetry configuration space using {NMR} restraints and van der
  {Waals} packing.
\newblock {\em Proteins: Structure, Function and Bioinformatics},
  2006; 65(1):203--219.

%\end{Enumerate}

%\end{thebibliography}

\end{Enumerate}

%\end{thebibliography}
%%%%%%% endpapers/biblio


%\input{papers}
%\input{papers2}

\MEMS{Change URL}

\gobble{
\begin{center}
{\sf Publications available online at {\tt www.cs.dartmouth.edu/\lower1.50ex\hbox{\LARGE{\~{}}}brd/Research/Bio/}}
\end{center}
}

%\newpage
%\setcounter{page}{1} % or whatever

\subsection*{C. Research Projects and Funding}

\subsection*{CURRENT SUPPORT}

\def\myhrule{\smallskip\hrule\smallskip}

\myhrule 
\noindent \begin{tabular}{ll}
DONALD, BRUCE R.	&		ONGOING\\
	(PI: Donald)	&	2002-2007	\\
	NIH/NIGMS & R01 GM-65982\\
{\em Automated NMR Assignment and Protein Structure}\\
\effortamount{\$150,000 &\\}
\end{tabular}

The long-term objective of this project is the development of new
computational methods for biomolecular NMR, to be applied in
structural genomics. Two main foci are novel algorithms for automated
assignments, and algorithms for automated structure determination from
solution-state protein NMR.

\myhrule 
\noindent \begin{tabular}{ll}
DONALD, BRUCE R.&			ONGOING \\
(PI: A. Anderson,     Co-investigator: B. Donald) & 2003-2008\\
NIH (NIGMS \& NIAID) &
R01 GM-067542   \\
{\em Design of C.~parvum and T.~gondii DHFR-TS Inhibitors}\\
\effortamount{\$150,000 {(total); Donald sub only: \$11,000.} & \\}
\end{tabular}

The major goal of this project is to design selective and potent
inhibitors against the dihydrofolate reductase (DHFR) domain of
dihydrofolate reductase-thymidylate synthase (DHFR-TS) from
{\em Cryptosporidium hominis} and {\em Toxoplasma gondii.  }

\myhrule 

\subsection*{Completed Research Support}
 
\myhrule
\noindent
\begin{tabular}{ll}
DONALD, BRUCE R.	&		COMPLETED\\
	(PI: Donald)	&	2003-2005 \\
	NSF	& EIA-0305444\\
{\em Algorithmic Challenges in Computational Biology}\\
\effortamount{        \$37,500 &\\}
\end{tabular}

This grant supported computational research in functional genomics and
computational methods in NMR structural biology.

%\myhrule

%\newpage

\myhrule

\noindent
\begin{tabular}{ll}
DONALD, BRUCE R.	&		COMPLETED\\
	(co-PI: B.~Donald)	&	1998-2003 \\
	NSF	& NSF 98-02068 \\
\end{tabular}

{\em Systems Science for Physical Geometric Algorithms}


NSF research infrastructure grant. The major goals of this project
were to provide research infrastructure for computational science and
computational biology in the Computer Science Department.  This
includes workstations, supercomputing facilities, networking, etc.

\myhrule

\newpage

\myhrule

\noindent
\begin{tabular}{ll}
DONALD, BRUCE R.	&		COMPLETED\\
	(PI: Donald)	&	2001-2003 \\
	NSF	& EIA-0102710\\
\end{tabular}

{\em Physical Geometric Algorithms and Systems for
        High-Throughput NMR Structural Biology}

  The major goals of this project were to
develop novel computational methods for biomolecular NMR.

\myhrule


\noindent
\begin{tabular}{ll}
DONALD, BRUCE R.	&		COMPLETED\\
	(PI: Donald)	&	2001-2003 \\
	NSF	& EIA-0102712\\
\end{tabular}

{\em Physical Geometric Algorithms and Systems for
        Structural Biology using Mass Spectrometry}

The major goals of this project were to
develop novel computational methods for structural mass
spectrometry and proteomics.

\myhrule

\noindent
\begin{tabular}{ll}
DONALD, BRUCE R.	&		COMPLETED\\
	(PI: Donald)	&	2000-2006 \\
	DHS/ODP	& 2000-DT-CX-K001
\end{tabular}

{\em Microelectromechanical Systems for Infosecurity}


The major goal of this project was the development of novel
microelectromechanical systems ("MEMS") to be useful in micro- and
nano-technology applications for homeland security, in particular,
information security and micro robotics.

\myhrule



\subsection*{PENDING SUPPORT}


\myhrule 
\noindent \begin{tabular}{ll} DONALD, BRUCE R.& PENDING \\
 (PI: D. Madden, Co-investigator: B. Donald) & 2007-2012\\
Submitted to NIH (NIDDK) & R01 Application \\
 {\em Keeping CFTR in its
Place: An Integrated Small-Molecule Approach}\\
\end{tabular}

The major goal of this project is to develop an integrated
experimental and theoretical approach to identifying small-molecule
inhibitors selective for the CAL PDZ domain (a molecular scaffolding
protein), which interacts with the cytoplasmic C-terminus of the
cystic fibrosis transmembrane conductance regulator protein (CFTR).
 

\myhrule 
\noindent \begin{tabular}{ll} DONALD, BRUCE R.& PENDING \\
 (PI: J. Hoch, Co-PIs: B. Donald, G. Wagner, A. Alexandrescu,
 P. Bolton) & 2006-2008\\ 
Submitted to NSF & MRI application \\
{\em	Acquisition of a High Perfomance Computational
Resource for NMR Structural Biology}.&\\
\end{tabular}

The major goal of this project is the acquisition of a supercomputer
that will be attached to a high field NMR spectrometer in order to
facilitate the development of data-directed high-throughput
computational protocols for NMR data processing, automated assignment,
and structure determination.

\myhrule 

\noindent \begin{tabular}{ll} DONALD, BRUCE R.& PENDING \\
 (PI: B. Donald) & 2007-2012\\
Submitted to NIH (NIGMS) & R01 Application \\
 {\em Computational Active-Site Redesign and Binding Prediction via Molecular Ensembles}\\
\end{tabular}

The major goal of this project is to develop novel algorithms to plan
structure-based site-directed mutations to a protein's active site in
order to modify its function.  The new algorithms will make progress
towards the long-term objective of reprogramming the specificity of
non-ribosomal peptide synthetase domains, whose products include
natural antibiotics, antifungals, antivirals, immunosuppressants, and
antineoplastics.


\myhrule 

 
\end{document}

%%% Local Variables:
%%% write-file-hooks:   (time-stamp)
%%% time-stamp-active:  t
%%% time-stamp-start:   "\\\\def\\\\mydate{"
%%% time-stamp-end:     "}"
%%% time-stamp-line-limit: 20
%%% End: